In a second example, we tested for the presence of a single common genetic factor of neuroticism using summary statistics from 12 item-level indicators from UK Biobank (UKB; Supplementary Table 1) as estimated using the Hail software.22 Model fit was good (χ2[54] = 4884.10, AIC =4932.11, CFI = .893, SRMR = .109). Results indicated strong positive loadings for all indicators (Supplementary Figure 2). We used this single common factor model for both neuroticism and the p-factor when estimating SNP effects for discovery under the section SNP Effects, below.
