median switch error rate of 0.229%. We also used a subset of 397 of these trios that also had no third-degree relatives and obtained a median switch error rate of 0.234%. These error rates are similar to those produced by other phasing methods that can handle data at this scale42,43. Investigations on the effect of sample size on phasing performance and downstream imputation performance suggest that differences between methods will have negligible effect on genotype imputation and GWAS42.