Consecutive patients aged 50 years or older with a first-ever acute ischemic stroke at Huadong Hospital Affiliated to Fudan University between May 2012 and January 2013 were recruited. All patients underwent neuropsychological and neuroimaging assessments, and those who met the criteria for vascular MCI were included (n = 13) [29, 30]. 13 age- and sex-matched healthy controls were enrolled in this cross-sectional study. All subjects were right handed and had normal vision. This study was approved by Huadong Hospital Affiliated to Fudan University Ethics Board, and all subjects gave written, informed consents before participation.