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Chunk #30 — Results — Meta-analysis of depression in GS:SFHS and UKB

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Genome-wide meta-analyses of stratified depression in Generation Scotland and UK Biobank.
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within phenotype by genomic positions according to UCSC hg19/NCBI Build 37 Trait SNP CHR POS A1/A2 Freq β(se) P Direction Genes MDDrs563905034187552576T/C0.110.13 (0.03)9.08E–07++ FAT1 rs2964802510820843T/C0.280.09 (0.02)6.73E–07++-rs110333031135871266A/G0.370.09 (0.02)2.37E–07++-rMDDrs22914793178174944A/C0.4−0.10 (0.02)9.65E–07---rs10959631911220986T/C0.2−0.12 (0.02)8.34E-07---rs110333031135871266A/G0.370.11 (0.02)6.02E–07++-rs443817213111448658A/T0.250.11 (0.02)8.72E–07++-fMDDrs9648182713794849A/T0.12−0.17 (0.03)9.14E–08-- - rs17176546781880914A/G0.040.26 (0.05)7.93E–07++ CACNA2D1 mMDDrs1157361671155266609C/G0.02−0.46 (0.09)1.54E–07-- PKLR rs4478037333160407A/G0.080.29 (0.05)2.29E–08++ CRTAP rs1134850901173572495A/G0.04-0.32 (0.06)2.05E-07-- MRPL48 rs13805511524124704A/G0.15-0.18 (0.04)3.96E-07---Column A1/A2 contains the reference and alternate alleles for the index SNP, respectively. The meta-analysis minor allele frequency (Freq) and regression coefficient (β) columns pertain to the reference allele (A1). Chr and Position denote the location of the index SNP. SE is the standard error for β. The direction of effect of the index SNP in GS:SFHS and UKB is shown in the Direction column. The final column, Genes, indicates protein-coding reference sequence genes within 10 kb of the associated loci