to create well-powered polygenic scores in this ancestral population. Although we attempted to mitigate this issue with the PRS-CSx (Ruan et al., 2022) method, which integrates GWAS summary statistics of European ancestry and African ancestry populations to improve the performance of PRS, the predictive power of PRS in the AA sample was still attenuated. Accordingly, our findings should be viewed as initial evidence, and the question of whether and how genetic factors predict variability in individuals’ response to common family stressors in non-European populations merits further investigation.
