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Chunk #22 — Discussion

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A GABRA2 polymorphism improves a model for prediction of drinking initiation.
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The inclusion of the high-risk TT genotype of GABRA2 rs279871 resulted in model improvement even after adjusting for other substantial predictors, such as MBFD, number of CD symptoms, externalizing problems, a family history of AD, and covariates of sex, age, and ancestry. The recessive genetic model performed better than the additive genetic model. G X E interactions were not supported.