identified 3593 probes representing 3593 genes to construct the co-expression network. Finally, we exported the network of the interesting genes with Topology Overlap Matrix (TOM) value > 0.15. We visualized the networks by Cytoscape [48]. Due to that the TOM value could not exhibit the positive or negative correlation between co-expressed genes, we defined the signed expression similarity as the value of the correlation coefficient between the profiles of genes i and j: sij = cor(xi,xj). Person correlation coefficient was calculated by using R software.
