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Chunk #8 — Results — SNP fine mapping on chromosome 2q

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COGA phenotypes and linkages on chromosome 2.
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We chose to follow up on these chromosome 2 results, especially in the area around 250 cM, with further analyses using the Affymetrix SNP data. We examined the evidence for linkage using only the SNP data for all of chromosome 2. The linkage results for the EEG principal component outcome is shown in Figure 4 and that for latent variable principal component is shown in Figure 5. These results confirm the short tandem repeat (STR) evidence for linkage to the 250-cM region just before the q-terminus for these outcome variables, though the peak signal shifted centromerically to ~220 cM.