Table 4 shows the ANCOVA results for the two SNPS tested. The model testing the acute adaptive response to alcohol that included the GABRA2 SNP rs279858 found recent drinking history was associated with acute tolerance (p=0.01). In addition, there was a recent drinking history x genotype interaction (p=0.01). The model that included the GABRG1 SNP rs1497577 demonstrated no significant effects (all p>0.13).