Chunk #37 — Factors to Consider When Modeling FASD — Finding the right control group

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A comparison of the different animal models of fetal alcohol spectrum disorders and their use in studying complex behaviors.

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Rodent models using the liquid diet model of ethanol exposure, where pair-fed animals consume a liquid diet with maltose dextrin substituted for the ethanol-derived calories, show varying results in pair-fed animals, with some studies showing deficits (128, 141, 142), and others showing no differences between pair-fed animals and controls (88, 143, 144).