In one study, DTI in alcoholics with (n = 7) and without (n = 20) WKS showed FA deficits in the fornix and cingulum bundle of the Papez or medial limbic circuit, measured using tract-based spatial statistics (TBSS). These FA effects were greater in alcoholics with WKS relative to those without it (Segobin et al. 2015). The number of tracts in the fornix appears to be reduced only in WKS patients (Nahum et al. 2015).
