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Chunk #24 — Results — Published data: Association testing

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Power and predictive accuracy of polygenic risk scores.
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the power would be 38% if the trait is fully explained by the markers, but under a more conservative model in which the explained genetic variance is 30%, the power is just 8% and increases to 13% under an even split of training and testing samples. Again, splitting a single GWAS sample does not admit high power for testing a polygenic score.