Development of methods and tools related to pathway analysis is ongoing and dynamic. In particular, because pathways are of broad interest, targeted adaptations to their associated databases would expand their utility for investigators from a variety of backgrounds. These adaptations might include simpler search and download mechanisms, consistency in pathway names and classifications, and methods for describing pathway overlap. In addition, a universal format for annotation files might encourage interoperability among analytical tools, allowing investigators flexibility to precisely match their databases and statistical methods of choice.
