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Chunk #31 — RESULTS — Quantity

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Can we identify genes for alcohol consumption in samples ascertained for heterogeneous purposes?
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yes

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In the younger dataset, a peak with a LOD of 2.1 was found on chromosome 1 at marker D1S2667 (between D2S1612 and D1S199). This peak was maximal for the sample containing fewest light drinkers and declined as more light drinkers were included in the sample. No linkage was found when analysing the older dataset. Also in the younger dataset, a LOD of 2.05 was found on the X chromosome at marker DXS6800 (between DXS8029 and DXS6789). This peak was maximal for the full sample and decreased as increasing numbers of light drinkers were dropped from the sample. A small peak (LOD = 1.4) was also found using the older dataset, full sample. In addition, a minor peak, with a LOD of 1.6, was found on chromosome 6 at ATA28B11, using the older dataset and reduced light drinkers.