The datasets (Supplementary Figure 1) used in this study comprise the OCD Psychiatric Genomics Consortium sample and are fully described in primary publications (Stewart et al. 2013; Mattheisen et al. 2015; International Obsessive Compulsive Disorder Foundation Genetics Collaborative (IOCDF-GC) and OCD Collaborative Genetics Association Studies (OCGAS) 2017). All participants over 18 and the parents of participants under 18 gave written informed consent and this work was approved by the relevant institutional review boards at all participating sites. Participants of European ancestry were selected for this study and include cases and controls from Dutch, South African, European, and Ashkenazi Jewish ancestries. Additionally, trio samples were included in the meta-analysis and consisted of proband cases and pseudo-controls. The pseudo-controls were derived from the non-transmitted parental chromosomes.
