Chunk #27 — Results — Demographic and clinical characteristics — Predictor evaluation and brain regions that contributed most to the SVR prediction in data set 1
The SVR prediction results demonstrated that ReHo values can serve as a predictor of addiction severity in patients with AUD. Specifically, the ReHo values could predict MAST scores (R2 = 0.29; P = 1.96 × 10−3; MAE = 3.61; permutation tests P = 0.005; Fig. 2A), AUDIT scores (R2 = 0.38; P = 2.80 × 10−4; MAE = 3.11; permutation tests P = 0.005; Fig. 2B). The contributed most to the SVR prediction model for MAST scores included the right NACC, right putamen, left insula, right putamen pre-SMA, right dACC, left OFC and left superior temporal gyrus. Similarly, the contributed most to the SVR prediction model for AUDIT scores included the right NACC, right putamen, right caudate, right putamen pre-SMA, right dACC, left OFC and left medial temporal gyrus(Fig. 2C, D).
