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Chunk #30 — Discussion

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Combined role of childhood maltreatment, family history, and gender in the risk for alcohol dependence.
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in the presence of parental history and female gender but differ by whether childhood sexual abuse or emotional neglect was experienced. Results support and enhance our understanding of the hypothesis that the effect of parental history on complex disorders may depend on childhood maltreatment and gender. Given the importance of genetic factors in the development of alcohol dependence (Gelernter & Kranzler, 2009), these results suggest directions for future investigations involving more genetically informative samples.