Another area of potential for future research is applying the existing literature on dyadic physiological and neuroendocrine co-regulation to the alcohol field, an effort that has begun but needs to be extended. Data collected from samples of couples experiencing relationship distress and who enrolled in treatment trials for problems other than AUD indicate that discordant dyadic autonomic dysregulation is associated with acute and more severe couple conflict,97 whereas synchrony in autonomic functioning is indicative of constructive couple therapy processes such as working alliance and improved health outcomes.98 As biofeedback intervention approaches continue to evolve in the AUD field, these emerging data can help to inform the development and refinement of remote and in-person dyadic biofeedback to support recovery efforts among families affected by AUD.