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Chunk #2 — Introduction

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SEQMINER: An R-Package to Facilitate the Functional Interpretation of Sequence-Based Associations.
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The statistical package R is a popular platform for data analysis and methodology development. In order to facilitate the development of new methods in R for the functional interpretation of genotype‐phenotype associations, we developed the R package SEQMINER with a variety of useful features: first, SEQMINER supports variant annotation and data integration for whole‐genome datasets of summary association statistics. Second, SEQMINER allows efficient random access and queries for sequence datasets, files of summary association statistics, and files for the correlation coefficients between summary association statistics. Retrieved information can be automatically parsed and made ready for downstream analysis. Finally, SEQMINER is self‐contained and optimized for statistical genetics analyses of summary association statistics. Many commonly used features in statistical genetics can be performed using a minimum of steps, which considerably expedites the analyses and method development.