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Chunk #3 — I. Introduction

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The relationships of the level of response to alcohol and additional characteristics to alcohol use disorders across adulthood: a discrete-time survival analysis.
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relationship between FH and adverse alcohol outcomes (Cotton, 1979; Jacob et al., 2003; Jennison & Johnson, 1998; Ohannassian et al., 2004; Schuckit et al., 2005; Schuckit & Smith, 2000). The familial pattern of AUDs is also associated with an earlier onset of drinking, which itself predicts a higher risk for future alcohol-related difficulties (Grant & Dawson, 1997; McGue et al., 2001; Obot et al., 2001; Prescott & Kendler, 1999; Seljamo et al., 2006; Warner et al., 2007; York et al., 2004). Earlier onset of alcohol use also relates to a range of additional problems including physical fights, driving arrests, drug use, and other antisocial behaviors (Hingson et al., 2001; King & Chassin, 2007; Kuperman et al., 2001; McGue et al., 2001). Studies have reported that once drug use and antisocial characteristics are considered, the relationship between an early onset of drinking and alcohol outcomes is likely to diminish (Dawson et al., 2008; King & Chassin, 2007; Kuperman et al., 2001; Labouvie & White, 2002).