Quantitative studies of brain structure and motor function have revealed the traditionally accepted relationship between postural instability and small volume of the anterior superior cerebellar vermis in alcoholics (Sullivan et al., 2000b), infratentorial tissue volumes (Sullivan et al., 2010a), and postural sway (Sullivan et al., 2006a). Components of sway may be the consequence of damage to other nodes in the frontocerebellar circuit. For example, using posturography and balance platform testing, truncal tremor was observed at two frequencies in alcoholic men (Sullivan et al., 2006a): the tremor at 5-7 Hz could indicate direct damage to the thalamus (Guehl et al., 2003).
