under review). The consideration of smoking status and volume is a relatively recent trend in alcohol research, with most research to date comparing cases with high levels of alcohol abuse, or specific organ damage (e.g., cirrhosis), to normal controls. Our aim is to develop additional case-control cohorts that, along with the impact of tobacco smoking on ARBD, allow a wider range of research questions to be addressed. Cohorts in development are subjects with different drinking patterns or pathologies, such as heavy drinkers who do not endorse DSM-IV criteria for addiction, older drinkers with comorbidities (i.e., diabetes), alcoholic smokers and non-smokers, and alcoholics with suicidal behavior.
