Chunk #44 — Results — Latent class analysis — Model comparisons

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The CHRNA5/A3/B4 gene cluster and tobacco, alcohol, cannabis, inhalants and other substance use initiation: replication and new findings using mixture analyses.

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The early onset class of the 3-class model contained 14.6% of the subjects, followed by 39.9 and 45.5% for the medium and late onset classes. Class proportions in the 4-class model were 11.5, 16.33, 32.9 and 39.3%. The fit indices of the models, and the estimated mean age of first use in the 3-class model are presented in Tables 4 and 5, respectively.