Brain samples were obtained from 134 individuals of European descent. All individuals were neurologically normal during life and confirmed to be neuropathologically normal by a consultant neuropathologist using histology performed on sections prepared from paraffin-embedded brain tissue blocks. The individuals sampled had a mean age at death of 59 years old (range 16–102), were mostly men (74.5%) and the most common cause of death was ischemic heart disease (44.7%).