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Chunk #3 — Methods — ENCODE ChIA-PET

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Obesity-associated variants within FTO form long-range functional connections with IRX3.
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Publicly-available data for the breast cancer MCF7 cell line, generated by as part of the ENCODE project38 were downloaded from and visualized with the WashU EpiGenome Browser39 (http://epigenomegateway.wustl.edu/browser/). Li and colleagues40 performed ChIA-PET to capture long-range chromatin interactions associated with RNA polymerase II.