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Chunk #54 — Online Methods — Step 1: Direct IBD-based phasing using long IBD

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Fast and accurate long-range phasing in a UK Biobank cohort.
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yes

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match. At the end of the procedure, all remaining pairs of trimmed matches are consistent. We then perform a final check for global consistency of implied phase orientations among all matches, i.e., we reduce (if necessary) to a subset of matches that can each be assigned to either a surrogate maternal haplotype or a surrogate paternal haplotype in a manner that respects pairwise constraints (a) and (b).