To examine the genetic correlation47 of COPD and asthma over the entire genome, we performed LD score regression46 using summary statistics from publically available asthma GWAS data from the GABRIEL Consortium43. For all comparisons using LD score regression, we filtered to HapMap3 variants, limited to European-ancestry subjects with genome-wide data, and filtered on missingness using default parameters in munge_sumstats.py. For the GABRIEL data, we required a variant to be present in at least 35 of the studies.
