paperKB
coga / coga-kb
Help
Sign in

Chunk #20 — ONLINE METHODS — Genotyping, quality control and imputation

Source
Meta-analysis and imputation refines the association of 15q25 with smoking quantity.
Embedded
yes

Text

We imputed all SNPs reported in the CEU sample in HapMap Phase II using various imputation algorithms12,37 (see the URL section for a link to the software ProbABEL). Imputations were performed after excluding samples and SNPs that did not meet the study-specific quality control criteria. Genotypes were imputed for SNPs not present in the genome-wide arrays or for those where genotyping had failed to meet the QC criteria.