A112G-MOPR knock-in mice were generated on C57BL/6 genetic background in Dr. Blendy’s laboratory. The animals (8–15 weeks, 18–30 g) were housed in the University of Pennsylvania animal facility and maintained on a 12 h light/dark cycle with ad libitum access to food and water. Animals were used in accordance with the methods approved by University of Pennsylvania Animal Care and Use Committee. Mice homozygous for the A112 or G112 allele are used for the study.
