across small regions by computing a rolling window sum across the genomic region for each group of cells (using a window size of 100 bp by default). This was implemented in the CoveragePlot function in Signac. We also implemented an interactive version of the CoveragePlot function using the Shiny Gadgets framework in R (https://cran.r-project.org/package=shiny) as the CoverageBrowser function in Signac. The interactive CoverageBrowser provides the same functionality as CoveragePlot, but additionally allows interactive navigation to different genomic regions and dynamic regrouping of cells.