Here, N is the total number of nodes. The human brain processes information in a specific manner while each brain region processes a specific kind of information; this is called the segregation of information. The local efficiency and clustering coefficient are the network measures used for this purpose. Clustering coefficient (CC) quantifies the intensity of the neighbors of the connected nodes in a network [6]. (4)CC=1N∑h∑i,jaijaihajhdh(dh−1) where dh is the degree of the node and aij is a member of the connectivity matrix.