[7], ABCA7 [8, 9], and SORL1 [10, 11] that are associated with AD and confer risk comparable to that of carrying one APOE ε4 allele. Besides age at onset, the clinical presentations of LOAD and ADAD are remarkably similar with an amnestic and cognitive impairment phenotype [12, 13]. A minor fraction of cases of ADAD have additional neurological findings, sometimes also seen in LOAD [12, 13].
