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Chunk #8 — Historical Perspectives — Comparative Studies on the Effects of Cannabis and Ethanol

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A review of the interactions between alcohol and the endocannabinoid system: implications for alcohol dependence and future directions for research.
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of deep-stage slow-wave sleep and an increase in REM following cessation of ethanol use, while chronic cannabis users show an increase in time spent in REM sleep. In the case of alcoholic patients, the alterations in sleep architecture seem to be more severe than in chronic cannabis users, and they can persist for many months into abstinence. In either case, resumption of drug use acts to normalize sleep patterns.