To validate the association signals from the CLOZUK + PGC meta-analysis, we amalgamated data contributed by other schizophrenia genetics consortia (total of 5,762 cases and 154,224 controls; details in the Supplementary Note). We sought GWAS summary statistic data for the index SNPs from the 50 new genome-wide significant loci (Supplementary Table 4). These summary statistics were subjected to meta-analysis in METAL using the fixed-effects procedure to obtain replication and heterogeneity statistics (Supplementary Table 6).
