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Chunk #78 — Methods — Statistical analyses

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Single nuclei transcriptomics in human and non-human primate striatum in opioid use disorder.
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quality control metrics) or derived metrics (AUCell gene activity scores) are repeated measurements of the same cohort of human individuals or rhesus macaque subjects. Metrics that are differentially expressed across multiple cell type conditions are reported and summarized at the largest significant adjusted P-value and lowest effect size magnitude. Genes or metrics that are only significantly differentially expressed across one cell type are reported with exact adjusted P-values and effect sizes rounded to 2 significant digits. Exact P-values and effect sizes are reported in the supplementary data. All statistical analyses performed use two-sided test statistics.