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Chunk #13 — DISCUSSION

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Fast and accurate genotype imputation in genome-wide association studies through pre-phasing.
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Overall, our results show that pre-phasing provides comparable accuracy to state-of-the-art imputation methods. While Tables 1 and 2 focus on selected combinations of data and methods, we also find that minimac and IMPUTE2 produce very similar trends in accuracy and running time when applied to the same dataset (for details, see Supplementary Fig. 4 and compare Table 1 and Supplementary Table 1).