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Chunk #6 — Introduction

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Bayesian test for colocalisation between pairs of genetic association studies using summary statistics.
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These limitations motivate the development of novel methodologies to test for colocalisation between pairs of traits. Here, we derive a novel Bayesian statistical test for colocalisation that addresses many of the shortcomings of existing tools. Our analysis focuses on a single genomic region at a time, with a major focus on interpreting the pattern of LD at that locus.