This work was supported by the National Institutes of Health’s National Institute on Alcohol Abuse and Alcoholism (P50AA005595 & K01AA021145) and National Institute on Drug Abuse (K01DA036681). The supporting organizations had no role in study design, data collection, data analysis, interpretation of results or decision to submit the manuscript for publication. The content of this paper is the sole responsibility of the authors and does not reflect official positions of NIH, NIAAA or NIDA.