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Chunk #18 — RESULTS — Main effects of polygenic score and relationship status

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Polygenic risk for alcohol misuse is moderated by romantic partnerships.
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Table 2 provides the estimates for the linear mixed models evaluating the joint effect of GPS and relationship status. In the model for main effects (model 1), those currently in a relationship had lower levels of intoxication frequency, but not drinking frequency or AD symptoms. GPS remained significantly associated with each of these alcohol-related behaviors.