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Chunk #97 — Supplementary information

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Analysis of gene expression in the postmortem brain of neurotypical Black Americans reveals contributions of genetic ancestry.
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Supplementary InformationSupplementary Methods, Figs. 1–45, Tables 1–6 and Data 3–15. Reporting Summary Supplementary Data 3Excel file of Gene Ontology (GO) term enrichment and gene set enrichment analysis (GSEA) for genetic-ancestry (continuous) DEGs across the caudate nucleus, dentate gyrus, DLPFC and hippocampus. Supplementary Data 4Excel file of GO term enrichment for genetic ancestry-associated WGCNA modules across brain regions. Supplementary Data 5Compressed directory of ancestry-associated DEGs enriched for WGCNA module functional enrichment results (that is, GO term enrichment) for the caudate nucleus, dentate gyrus, DLPFC and hippocampus. Supplementary Data 7Compressed text file of genetic ancestry-dependent eQTL results (LFSR < 0.05), variant–feature pairs across the caudate nucleus, dentate gyrus, DLPFC and hippocampus for four features (gene, transcript, exon, junction). Supplementary Data 8Compressed directory of PDF of scatter plots comparing DNA methylation association with local and global ancestry for the caudate nucleus, DLPFC and hippocampus. Plots are annotated with the genetic ancestry DMR test results. Supplementary Data 9Excel file of GO term enrichment for genetic ancestry differential methylation regions across the caudate nucleus, DLPFC and hippocampus. Supplementary Data 10Excel file of stratified LD score