Although psychosis is a characteristic feature of schizophrenia, it is not specific and not isolated. One of the other features is disorganization. Unfortunately there is no clear report of disorganization in WM diseases. This could be related to a reporting bias, as neurologists may not recognize or describe mild disorganization. Indeed, we were able to observe one patient scoring 4 on the Positive And Negative Syndrome Scale (PANSS) disorganization subscore. The symptom lasted during a relapse of her MS, and was accompanied by a clear reduction in executive attention without confusion or mood disorder. However, more observations arc required in order to conclude.