There are several examples of differences in sweet taste preferences among species of vertebrate animals. Despite nearly universal preference for sugars, the chicken and Felidae species (domestic cat, tiger, lion and cheetah) are not attracted to sugars and other sweeteners.[64-69] Mammals also differ in preferences for artificial sweeteners, for example aspartame.[70,71] Species variation in the T1R receptors plays prominent role in these differences in sweet taste preferences.