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Chunk #24 — Materials and Methods — Bioinformatics analyses

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Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence.
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Linkage disequilibrium structure was discerned using LocusZoom41 or Haploview42 with reference to the 1000 Genomes populations of European-ancestry (denoted EUR). SNP annotations were taken from the Ensembl genome browser.43