Chunk #30 — 4. Discussion — 4.1. Altered Functional Connectivity in the Memory Group — 4.1.1. Predominant Hyperconnectivity of Low-Frequency Oscillations in the Memory Group
delta and theta bands, as compared to controls [82]. Such alterations in resting-state EEG connectivity in slow rhythms (delta and theta) have also been reported in childhood developmental disorders, such as autism spectrum disorders [83] and specific learning disorders [84]. On the contrary, healthy aging is marked by decreased slow frequency activity (band power) in the delta and theta bands during the resting state [85], as well as by reduced EEG network connectivity [86]. On the other hand, while performing tasks, both delta and theta band oscillations predominantly contribute to the generation of P300 or P3 [87], a prominent event-related potential (ERP) component that is a marker of contextual neural processing, the amplitude of which is reduced abnormally in individuals with and/or at risk for AUD, who have shown reduced amplitudes [9]. Interestingly, slow delta and theta oscillations are often found to be attenuated during task performance in individuals with chronic AUD relative to healthy individuals [88], while these slow theta oscillations are also involved in episodic memory maintenance processes during cognitive processing [89].
