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Chunk #4 — Methods (for on-line version only) — Brain-expressed genes

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De novo mutations revealed by whole-exome sequencing are strongly associated with autism.
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A list of brain-expressed genes was obtained from expression array analysis across 57 postmortem brains (age 6 weeks post conception to 82 years) and multiple brain regions.23 Using this data 14,363 (80%) of genes were classified as brain-expressed (Supplementary Information).