rate of absorption of alcohol or cocaine in the nasal and gastro-intestinal mucosae (Fattinger et al., 2000; Norberg et al., 2003). The higher social acceptability of nicotine use compared to other substances also increases the exposure to environmental, situational and sensorial cues that evoke craving for its consumption (Benowitz, 2008; Hatsukami et al., 2008). Furthermore, nicotine use does not produce the notorious disruptive behavioral changes that alcohol, cannabis and cocaine use often engender (Benowitz, 2008; Hatsukami et al., 2008).
