In this paper, we first sketch selected highlights gleaned from the 60 years of biomedical research into the genetics of alcohol drinking in rodents. We next review evidence on the genomic location of genes affecting ethanol preference drinking from QTL mapping studies in mice and rats, and present new information for two murine QTLs. Finally, we provide a progress report on a project creating a new mouse model for binge-like drinking, the High Drinking in the Dark (HDID) selected lines.
