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Chunk #44 — Discussion

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Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.
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For COPD, when controlling for cigarettes-per-day we did not find evidence for association with any of the loci after correction for multiple tests. For locus 1, the odds ratio of 1.12 (1.01–1.23) is lower than for smoking and lung cancer. The COPD analyses were based on smaller samples than those available for CPD or for lung cancer.