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Chunk #9 — ONLINE METHODS — Sensitivity analyses and phenotypic data quality checks

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New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism.
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To identify any studies that showed unusual relationships between birth weight and other phenotypes, we obtained from each study the percentage of variance in birth weight explained by each of sex, parity, maternal smoking, gestational age and maternal pre-pregnancy BMI as 100*adjusted-R2 value from linear regression of birth weight against each individual trait. The observed relationships between birth weight and each related trait were reasonably consistent across all of the 43 studies (see Supplementary Table 13 and Supplementary Figure 9).