From November September of 1997 through November of 2011, 1,556 persons agreed to participate and the baseline clinical evaluation has been completed on 1,489. Of these, 1,088 (73.1%) are women, 1,307 (87.8%) are non-Hispanic white, the mean age is 80.1 years and the mean education is 14.4 years. 1,409 (94.6%) were without dementia following the baseline clinical evaluation. All clinical evaluation forms have been translated into Spanish and of 80 Hispanics, 63 are being tested in Spanish.